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Register:	ClinicalTrials.gov
Last refreshed on:	16 December 2017
Main ID:	NCT03076099
Date of registration:	06/03/2017
Prospective Registration:	No
Primary sponsor:	Nan Jiang
Public title:	Dexmedetomidine on Post-operative Blood Pressure in Bain Arteriovenous Malformation Embolization
Scientific title:	Effects of Dexmedetomidine on Post-operative Blood Pressure in Patients Undergoing Brain Arteriovenous Malformation Embolization
Date of first enrolment:	January 1, 2016
Target sample size:	30
Recruitment status:	Recruiting
URL:	https://clinicaltrials.gov/show/NCT03076099
Study type:	Interventional
Study design:	Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Triple (Participant, Care Provider, Outcomes Assessor).
Phase:	N/A

Countries of recruitment
China

Contacts

Name:	Nan Jiang, PhD
Address:
Telephone:	86 20 28823350
Email:	NJiang_sysu@126.com
Affiliation:

Name:	Yi Liu, Master
Address:
Telephone:	+86 13632391455
Email:	liuyisysu@126.com
Affiliation:

Key inclusion & exclusion criteria

Inclusion Criteria:

- patients undergoing brain arteriovenous malformation embolization in the fist
affiliated hospital, Sun Yat-sen University, aged 18-65 years, available to chat
with,and the tracheal tube was extubated after surgery immediately.

Exclusion Criteria:

- abuse anesthetic analgesics and sedative drugs, or allergic to Dexmedetomidine or
other anesthetics, hypotension or bradycardia before surgery, severe pulmonary disease
with saturation of pulse oximetry less than 90% before surgery, or patients refused to
attend in this study.

Age minimum: 18 Years
Age maximum: 65 Years
Gender: All

Health Condition(s) or Problem(s) studied

Anesthesia

Intervention(s)

Drug: Dexmedetomidine

Other: normal saline

Primary Outcome(s)

urapidil consumption [Time Frame: the end of the 6th hour after tracheal extubation]

Secondary Outcome(s)

Quality of Recovery Score [Time Frame: the end of the 6th hour after tracheal extubation]

PONV at 48th hour [Time Frame: the end of the 48th hour after tracheal extubation]

Analgesics consumption [Time Frame: the end of the 6th hour after tracheal extubation]

Analgesics consumption on POD2 [Time Frame: the total consumption of urapidil on post-operative day 2.]

Bradycardia [Time Frame: the end of the 6th hour after tracheal extubation]

Bradycardia at 24th hour [Time Frame: the end of the 24th hour after tracheal extubation]

PONV [Time Frame: the end of the 6th hour after tracheal extubation]

urapidil consumption on POD1 [Time Frame: the total consumption of urapidil on post-operative day 1.]

Analgesics consumption on POD1 [Time Frame: the total consumption of urapidil on post-operative day 1.]

Quality of Recovery Score at 48th hour [Time Frame: the end of the 48th hour after tracheal extubation]

Visual Analogue score at 24th hour [Time Frame: the end of the 24th hour after tracheal extubation]

Visual Analogue score at 48th hour [Time Frame: the end of the 48th hour after tracheal extubation]

Visual Analogue score [Time Frame: the end of the 6th hour after tracheal extubation]

Bradycardia at 48th hour [Time Frame: the end of the 48th hour after tracheal extubation]

PONV at 24th hour [Time Frame: the end of the 24th hour after tracheal extubation]

Quality of Recovery Score at 24th hour [Time Frame: the end of the 24th hour after tracheal extubation]

urapidil consumption on POD2 [Time Frame: the total consumption of urapidil on post-operative day 2.]

Secondary ID(s)

NJiang2016-001

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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