Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02560467
• Date of registration: 22/09/2015
• Prospective Registration: Yes
• Primary sponsor: Oregon Health and Science University
• Public title: Perfusion Imaging With Myocardial Contrast Echocardiography in HCM
• Date of first enrolment: December 1, 2015
• Target sample size: 10
• Recruitment status: Active, not recruiting
• URL: https://clinicaltrials.gov/show/NCT02560467
• Study type: Interventional
• Study design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Diagnostic. Masking: None (Open Label).
• Phase: N/A

Countries of recruitment

United States

Key inclusion & exclusion criteria

Inclusion Criteria:

- Age 18-80 years

- Established diagnosis of HCM

Exclusion Criteria:

- Known history of coronary or peripheral artery disease

- History of myocardial infarction

- Pregnant or lactating females

- Hypersensitivity to any ultrasound contrast agent

- Evidence right-to-left or bi-directional intracardiac shunt

- Moderate or greater valve disease other than from HCM (systolic anterior motion of the
mitral valve)

- History of septal ablation or myectomy

- Hemodynamic instability

- Pacemaker dependent heart rhythm



Age minimum: 19 Years
Age maximum: 80 Years
Gender: All

Health Condition(s) or Problem(s) studied

Hypertrophic Cardiomyopathy

Intervention(s)

Drug: Echo and myocardial contrast echocardiography perfusion imaging

Primary Outcome(s)

Myocardial perfusion (ml/min/g) in the hypertrophied segment on myocardial contrast echo [Time Frame: One hour]

Myocardial blood flow reserve in the hypertrophied segment on myocardial contrast echo [Time Frame: One hour]

Secondary Outcome(s)

Spatial distribution of blood flow on myocardial contrast echocardiography [Time Frame: One hour]

Secondary ID(s)

15158

Source(s) of Monetary Support

Please refer to primary and secondary sponsors