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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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28 December 2015 |
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Main ID: |
NCT02351752 |
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Date of registration:
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27/01/2015 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy: a Self- Controlled Study
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Scientific title:
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Renal Division, Peking University First Hospital, Institute of Nephrology, Peking University, Key Laboratory of Renal Disease |
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Date of first enrolment:
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January 2015 |
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Target sample size:
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20 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02351752 |
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Study type:
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Interventional |
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Study design:
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Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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Phase:
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Phase 4
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Countries of recruitment
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China
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Contacts
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Name:
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Hong Zhang, PhD,MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Peking University First Hospital |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
1. primary IgA nephopathy
2. age 18-75 years
3. proteinuria range from 0.75 to 3.5g/d even after three-month treatment by sufficient
ACEi/ARB
4. eGFR>30ml/min/1.73m2
Exclusion Criteria:
1. immune suppressive agent in recent one years
2. crescent glomerulonephritis, might use immune suppressive agent
3. chronic hepatic disease
4. myocardial infarction
5. malignant hypertension
6. stroke
7. malignant tumor
8. retinopathy
9. other contraindication of Hydroxychloroquine
10. pregnancy and breastfeeding women
11. life expectancy for less than 6 months
12. in other clinical trials
13. not suitable for the study judged by investigator
Age minimum:
18 Years
Age maximum:
75 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Primary IgA Nephropathy
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Intervention(s)
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Drug: Hydroxychloroquine Sulfate
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Primary Outcome(s)
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proteinuia
[Time Frame: total four months(proteinic will recorded every 2 months )]
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Secondary ID(s)
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2014?851?
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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