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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.

Register:	ClinicalTrials.gov
Last refreshed on:	20 February 2023
Main ID:	NCT02278588
Date of registration:	28/10/2014
Prospective Registration:	Yes
Primary sponsor:	State University of New York at Buffalo
Public title:	Effect of 2.5 Years of Rasagiline Therapy on Progression of Cognitive Biomarkers Assessed by MRI in Parkinson's Disease.
Scientific title:	Effect of 2.5 Years of Rasagiline Therapy on Progression of Cognitive Biomarkers Assessed by MRI in Parkinson's Disease.
Date of first enrolment:	November 2014
Target sample size:	45
Recruitment status:	Completed
URL:	https://clinicaltrials.gov/show/NCT02278588
Study type:	Observational
Study design:
Phase:

Countries of recruitment
United States

Contacts

Key inclusion & exclusion criteria

IPD or HC subjects who were enrolled in a similar study about 2.5 years ago and for whom
Baseline DTI data are available.

Age minimum: N/A
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Parkinson's Disease

Intervention(s)

Drug: Rasagiline

Primary Outcome(s)

Change in cognitive biomarkers assessed by DTI [Time Frame: 2.5 years]

Comparison of change in cognitive biomarkers with change in MMSE and MoCA scores [Time Frame: 2.5 years]

Secondary Outcome(s)

Comparison of Baseline plasma BDNF with magnitude of change in brain cognitive biomarkers and MMSE and MoCA scores [Time Frame: 2.5 years]

Comparison of changes in plasma BDNF with changes in brain cognitive biomarkers and MMSE and MoCA scores [Time Frame: 2.5 years]

Secondary ID(s)

[616856-4]

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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