Computer-Based Balance Training for People With Parkinson's Disease

• Register: ClinicalTrials.gov
• Last refreshed on: 19 February 2015
• Main ID: NCT01162226
• Date of registration: 24/06/2010
• Prospective Registration: Yes
• Primary sponsor: University of California, San Francisco
• Public title: Computer-Based Balance Training for People With Parkinson's Disease
• Scientific title: "PD Wii: Computer-based Gait and Balance Training for Parkinson's Patients".
• Date of first enrolment: September 2010
• Target sample size: 62
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT01162226
• Study type: Interventional
• Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
• Phase: Phase 2

Countries of recruitment

United States

Contacts

• Name: Glenna A Dowling, PhD
• Affiliation: University of Ca San Francisco

Key inclusion & exclusion criteria

Inclusion Criteria:

1. presence of bradykinesia along with at least one of the following: muscular rigidity,
4-6 Hz rest tremor, and postural instability (Gelb, Oliver, & Gilman, 1999; Hughes,
Ben-Shlomo, Daniel, & Lees, 1992).

2. Hoehn & Yahr disease Stage 1 (unilateral disease) to 3 (mild to moderate bilateral
disease, physically independent) (Fahn and Elton, 1987).

Exclusion Criteria:

1. history of strokes, repeated head injury, encephalitis, oculogyric crises,
neuroleptic treatment, MPTP exposure, more than one affected relative, sustained
remission, strictly unilateral features after 3 years, supranuclear gaze palsy, early
severe autonomic involvement or dementia, Babinski sign, tumor, or a negative
response to L-DOPA (Hughes et al., 1992).

2. other neurologic, orthopedic or cardiac problems, cognitive impairment as evidenced
by 5 or more errors on the Mini Mental State Examination (MMSE) (Folstein, Folstein,
& McHugh, 1975)

3. visual or hearing impairments serious enough to interfere with their ability to
interact with the computer-based training program.



Age minimum: N/A
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Parkinson's Disease

Intervention(s)

Behavioral: gait and balance training program

Primary Outcome(s)

balance [Time Frame: 3 months]

gait [Time Frame: 3 months]

Secondary Outcome(s)

overall functional status [Time Frame: 3 months]

balance [Time Frame: 3 months]

falls [Time Frame: weeks 1-12]

subjective balance [Time Frame: 3 months]

Secondary ID(s)

2R42NS061502-02

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

National Institute of Neurological Disorders and Stroke (NINDS)