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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00598377 |
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Date of registration:
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31/12/2007 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Adrenal Functions in Autosomal Dominant Polycystic Kidney Disease
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Scientific title:
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Assessment of Adrenal Functions in Patients With Autosomal Dominant Polycystic Kidney Disease |
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Date of first enrolment:
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September 2006 |
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Target sample size:
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49 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00598377 |
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Study type:
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Interventional |
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Study design:
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Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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Phase:
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N/A
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Countries of recruitment
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Turkey
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Contacts
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Name:
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Rian Disçi, Professor |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Public Health |
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Name:
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Nese Çolak, Professor |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine Division of Endocrinology |
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Name:
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Bledi Çerkezi, Fellow |
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Address:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Radiology |
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Name:
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Kültigin Türkmen, Fellow |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine |
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Name:
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Tevfik Ecder, Professor |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University, Istanbul Medical Faculty, Department of Internal Medicine, Division of Nephrology |
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Name:
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Fatih Tufan, Fellow |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine |
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Name:
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Bora Uslu, Fellow |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine |
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Name:
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Mükremin Uysal, Fellow |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine |
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Name:
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Nilüfer Alpay, Fellow |
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Address:
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Telephone:
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Email:
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Affiliation:
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Istanbul University Istanbul Medical Faculty Department of Internal Medicine |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Healthy subjects
- Diagnosis of autosomal dominant polycystic kidney disease
Exclusion Criteria:
- A glomerular filtration rate below 60 ml/min
- History of recent major surgery
- Systemic infections with fever
- Significant hirsutism (Ferriman Gallwey score=8)
- Congenital adrenal hyperplasia
- Late onset congenital adrenal hyperplasia
- Systemic corticosteroid use (including previous use)
- Topical corticosteroid use
- Menstrual irregularity
- History of thromboembolism
- Uncontrolled diabetes or hypertension
- History of psychosis
- Pregnancy
- Lactation
- History of hypersensitivity to tetracosactin
Age minimum:
20 Years
Age maximum:
56 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Autosomal Dominant Polycystic Kidney Disease
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Intervention(s)
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Drug: Tetracosactin
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Primary Outcome(s)
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Inadequate response to tetracosactin infusion
[Time Frame: 30 and 60 minutes after the drug is administered]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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