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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00188188 |
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Date of registration:
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09/09/2005 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease
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Scientific title:
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Endothelial Dysfunction in Systemic Lupus Erythematosus: Its Contribution to Abnormalities in Coronary Perfusion. |
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Date of first enrolment:
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March 2002 |
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Target sample size:
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50 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT00188188 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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Phase:
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Phase 4
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Countries of recruitment
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Canada
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Contacts
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Name:
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Anne Cymet, RN |
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Address:
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Telephone:
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416-603-5800 |
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Email:
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anne.cymet@uhn.on.ca |
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Affiliation:
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Name:
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Anne Cymet, Rn |
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Address:
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Telephone:
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416-603-5800 |
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Email:
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anne.cymet@uhn.on.ca |
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Affiliation:
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Name:
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Robert M Iwanochko, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University Health Network, Toronto |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
>20 years Lupus according to ACR criteria Patients who demonstrate abnormality on
mycardial perfusion imaging are eligible for treatment arm of study
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Exclusion Criteria:
Steroid dependent asthma known contraindication to dipyridamole known intolerance to or
contraindication to use of ACE inhibitors history of angioedema serum creatinine.
200mmol/l Renal artery stenosis pregnant or breast feeding inability to perform low grade
exercise presently taking ACE, ARB or nitrates
Age minimum:
20 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Systemic Lupus Erythematosus
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Intervention(s)
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Drug: quinipril
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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