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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00135954 |
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Date of registration:
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25/08/2005 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Treatment of Patients With Idiopathic Membranous Nephropathy
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Scientific title:
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Treatment of Patients With Idiopathic Membranous Nephropathy at Risk for Renal Insufficiency: Comparison of Early Versus Late Start of Immunosuppressive Therapy |
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Date of first enrolment:
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July 1997 |
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Target sample size:
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29 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00135954 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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Phase:
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Phase 3
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Countries of recruitment
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Netherlands
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Contacts
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Name:
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Jack F Wetzels, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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Radboud University |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Idiopathic membranous nephropathy
- Serum creatinine < 1.5 mg/dl
- Nephrotic syndrome
Exclusion Criteria:
- Infection
- Instable angina
- Systemic disease
- Pregnancy
- Renal vein thrombosis
- Prior therapy with immunosuppressant agents
- Liver dysfunction
- Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
Age minimum:
18 Years
Age maximum:
75 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Glomerulonephritis, Membranous
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Intervention(s)
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Drug: Cyclophosphamide and steroids
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Primary Outcome(s)
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proteinuria
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side effects
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renal function (serum creatinine)
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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