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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00103597 |
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Date of registration:
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11/02/2005 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
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Scientific title:
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Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy |
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Date of first enrolment:
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January 2005 |
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Target sample size:
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50 |
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00103597 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment
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Phase:
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Phase 1
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Countries of recruitment
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Australia
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Contacts
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Name:
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Kerrie Schoffer, MBBS |
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Address:
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Telephone:
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Email:
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Affiliation:
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Movement Disorders Fellow |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Patients residing in Queensland Australia
- Age 40-95
- Parkinson's Disease or MSA diagnosed by a neurologist
- Symptoms of orthostatic hypotension, as defined by 2 validated questionnaires
Exclusion Criteria:
- Patients with acute cardiomyopathy or cardiac condition
- Patients unable to give consent
- Patients not stable on their Parkinsonian medications
- Patients with another cause for autonomic neuropathy
Age minimum:
40 Years
Age maximum:
95 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Orthostatic Hypotension
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Parkinson's Disease
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Multiple System Atrophy
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Intervention(s)
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Behavioral: Conservative Measures for Orthostatic Hypotension
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Drug: Fludrocortisone
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Drug: Domperidone
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Primary Outcome(s)
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Efficacy of conservative treatment, domperidone, and fludrocortisone for patient's subjective symptoms of orthostatic hypotension, and on objective autonomic testing
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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