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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT00002270 |
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Date of registration:
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02/11/1999 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection
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Scientific title:
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A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection |
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Date of first enrolment:
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October 1997 |
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Target sample size:
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Recruitment status: |
Completed |
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URL:
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http://clinicaltrials.gov/show/NCT00002270 |
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Study type:
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Interventional |
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Study design:
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Primary Purpose: Treatment
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Phase:
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N/A
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Countries of recruitment
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United States
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Key inclusion & exclusion criteria
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Inclusion Criteria
Patients must have:
- HIV seropositivity by both ELISA and Western blot.
- Biopsy proven progressive multifocal leukoencephalopathy (PML).
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions or symptoms are excluded:
- Intolerant to interferon.
- Prior or concomitant central nervous system disease (CNS) such as toxoplasmosis,
multiple sclerosis (MS), or neurosyphilis.
Patients with the following are excluded:
- Intolerant to interferon.
- Prior or concomitant central nervous system disease (CNS) such as toxoplasmosis,
multiple sclerosis (MS), or neurosyphilis.
Prior Medication:
Excluded:
- Patients receiving interferon for other reasons.
Age minimum:
18 Years
Age maximum:
65 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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HIV Infections
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Leukoencephalopathy, Progressive Multifocal
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Intervention(s)
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Drug: Zidovudine
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Drug: Interferon alfa-2b
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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