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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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1 April 2019 |
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Main ID: |
ChiCTR1900022243 |
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Date of registration:
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2019-03-31 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Effect of curcumin combined with probiotics on prevention and treatment in ileal pouchitis after operation of ulcerative colitis.
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Scientific title:
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Effect of curcumin combined with probiotics on prevention and treatment in ileal pouchitis after operation of ulcerative colitis. |
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Date of first enrolment:
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2019-04-01 |
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Target sample size:
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Experimental group:20;Control group:10; |
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Recruitment status: |
Recruiting |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=37542 |
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Study type:
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Observational study |
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Study design:
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Non randomized control
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Phase:
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0
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Countries of recruitment
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China
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Contacts
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Name:
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Gang Liu
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Address:
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154 Anshan Road, Heping District, Tianjin
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Telephone:
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+86 13389098101 |
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Email:
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landmark1509@163.com |
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Affiliation:
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Tianjin Medical University General Hospital |
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Name:
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Ting Zheng
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Address:
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154 Anshan Road, Heping District, Tianjin
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Telephone:
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+86 18202688924 |
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Email:
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zt2372314247@163.com |
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Affiliation:
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Tianjin Medical University General Hospital |
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Key inclusion & exclusion criteria
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Inclusion criteria: 1 Definitely diagnosed as UC and treated with IPAA, the postoperative time is more than 3 months;
2 Patients take probiotics regularly before being selected;
3 Aged 15 years and above;
4 Male or female;
5 Have given consent and the region is able to follow the patient who is treated;
6 Ability to record patients whose responses are answered in a regular follow-up.
Exclusion criteria: 1 Patients with kidney or liver disease, severe cardiovascular disease, chronic pancreatitis, diabetes or gallstones;
2 Postoperative pathology of IPAA surgery indicates that there is cancerous person;
3 Perform other surgical treatments or chemoradiotherapy and targeted therapy in the past 3 months;
4 Patients with laboratory abnormalities indicate anemia (hemoglobin <10), leukopenia, thrombocytopenia, and abnormal blood clotting;
5 Patients with infection, sepsis or pneumonia;
6 Pregnant or lactating women.
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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ileal pouchitis after operation of ulcerative colitis
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Intervention(s)
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Experimental group:Curcumin+Probiotics;Control group:Probiotics;
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Primary Outcome(s)
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Endoscopic score;
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Secondary Outcome(s)
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Blood routine;C-response protein;Fecal calprotectin;
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Source(s) of Monetary Support
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No
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Ethics review
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Status: Not approved
Approval date: 26/08/2013
Contact:
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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