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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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18 April 2017 |
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Main ID: |
ChiCTR-TRC-12002470 |
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Date of registration:
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2012-08-02 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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The effect of theophylline in the treatment of bronchiectasis, a random, double blind study
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Scientific title:
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The effect of theophylline in the treatment of bronchiectasis, a random, double blind study. |
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Date of first enrolment:
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2012-09-15 |
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Target sample size:
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1:46;2:46; |
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Recruitment status: |
Completed |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=7080 |
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Study type:
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Interventional study |
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Study design:
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Randomized parallel controlled trial
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Phase:
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Post-market
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Countries of recruitment
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China
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Contacts
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Name:
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Xu Gang
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Address:
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The respiratory mechanics laboratory of the first affiliated hospital of Guangzhou Medical University
510000
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Telephone:
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+86 13580375817 |
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Email:
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158572962@qq.com |
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Affiliation:
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The first affiliated hospital of Guangzhou Medical University |
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Name:
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Chen Rongchang
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Address:
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The respiratory mechanics laboratory of the first affiliated hospital of Guangzhou Medical University
510000
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Telephone:
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+86 13902273260 |
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Email:
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chenrc@vip.163.com |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: Patients between 18-65 years old with non-CF bronchiectasis,free from acute exacerbations for at least 3 months.
Exclusion criteria: Patients with a cigarette smoking history of more than 10 packs-year;
Patients with COPD;
Patients with traction bronchiectasis due to advanced fibrosis;
Patients with known intolerance for IC or theophylline;
Patients with asthma;
patients with other disease disturbing outcomes of the trials.
Age minimum:
15
Age maximum:
65
Gender:
Both
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Health Condition(s) or Problem(s) studied
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bronchiectasis not due to cystic fibrosis
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Intervention(s)
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1:theophylline;2:theophylline;
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Primary Outcome(s)
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St George's Respiratory Questionnaire;lung function;days needed SABA;Sputum culture;
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Secondary Outcome(s)
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Routine blood test;ESR;Induced sputum cytology count;IL-6;IL-8;TNF-alpha;Isoprostane;activity of HDAC;activity of HDTC;CRP;The Leicester Cough Questionnaire;24 hour sputum volume;the number of exacerbations;
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Source(s) of Monetary Support
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State Key Laboratory of Respiratory Research Institute for optional subjects
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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