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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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18 April 2017 |
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Main ID: |
ChiCTR-TRC-09000539 |
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Date of registration:
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2009-09-30 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Clinical studies of tacrolimus in idiopathic membranous Nephropathy with nephrotic syndrome therapy
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Scientific title:
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Clinical studies of tacrolimus in idiopathic membranous Nephropathy with nephrotic syndrome therapy |
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Date of first enrolment:
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2004-03-01 |
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Target sample size:
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S:10;L:10; |
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Recruitment status: |
Completed |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=8996 |
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Study type:
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Interventional study |
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Study design:
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Randomized parallel controlled trial
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Phase:
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Pilot study
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Countries of recruitment
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China
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Contacts
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Name:
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Li-ning Miao
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Address:
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No.218, Ziqiang Road, Changchun City, Jilin Province
130041
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Telephone:
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+86 13904303985 |
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Email:
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miaolining@yahoo.com.cn |
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Affiliation:
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Name:
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Hang Yuan
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Address:
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No.218, Ziqiang Road, Changchun City, Jilin Province
130041
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Telephone:
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+86 0431 88796526 |
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Email:
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hangyuan75@gmail.com |
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Affiliation:
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Second Hospital of Jilin University |
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Diagnosis of primary NS;
2. Renal biopsy-proven IMN and diagnosis of class I to III;
3. Scr<221umol/L;
4. No therapy with other immunosuppressive or non-steroidal anti-inflammatory drugs prior to the inclusion in the study.
Exclusion criteria: 1. Pregnancy;
2. Combined with serious complications such as severe infection, tumor, HIV infection, and active HBV infection;
3. Other serious renal disease including diabetic nephropathy;
4. Known allergy to the calcineurin inhibitors.
Age minimum:
16
Age maximum:
69
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Nephrotic Disease
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Intervention(s)
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S:Patients receive tacrolimus combined with prednison for six months;L:Patients receive tacrolimus combined with prednison for 24 months;
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Primary Outcome(s)
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Serum albumin level;24hours urinary protein;
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Source(s) of Monetary Support
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Social development division of Jilin Province
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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