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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.

Register:	ChiCTR
Last refreshed on:	18 April 2017
Main ID:	ChiCTR-TRC-09000338
Date of registration:	2009-02-23
Prospective Registration:	Yes
Primary sponsor:	The First Affiliated Hospital of Zhejiang University
Public title:	Full dose of RASS blockade versus steroids therapy in patients with IgA nephropathy
Scientific title:	Full dose of RASS blockade versus steroids therapy in patients with IgA nephropathy
Date of first enrolment:	2009-04-01
Target sample size:	Group A:60;Group B:60;
Recruitment status:	Completed
URL:	http://www.chictr.org.cn/showproj.aspx?proj=9193
Study type:	Interventional study
Study design:	Randomized parallel controlled trial
Phase:	Post-market

Countries of recruitment
China

Contacts

Name:	Chen Jianghua
Address:	79 Qingchun Road, Hangzhou, Zhejiang, China 31003
Telephone:	+86 0571 87236189
Email:	chenjianghua@zju.edu.cn
Affiliation:

Name:	Cheng Jun
Address:	79 Qingchun Road, Hangzhou, Zhejiang, China 310003
Telephone:	+86 0571 87236189
Email:	chengjunwood@sohu.com
Affiliation:	Kidney Disease Center of the First Affiliated Hospital of Zhejiang University

Key inclusion & exclusion criteria

Inclusion criteria: 1. biopsy-proven IgA nephropathy;
2. proteinuria (protein, 1.5 to 3 g/d);
3. eGFR>30ml/min/1.75m2;
4. Age 18-70 years;
5 Hypertention or untreated blood pressure >130/80mmHg.
Exclusion criteria: 1. Secondary IgA nephropathy;
2. Pathology-proven crecsentic glomerulonephritis.

Age minimum: 18
Age maximum: 70
Gender: Male

Health Condition(s) or Problem(s) studied

IgA nephropathy

Intervention(s)

Group A:Full dose of RASS blockade (ACEI and ARB blocker);Group B:prednisone ;

Primary Outcome(s)

Concentration of serum creatinin;

Secondary Outcome(s)

Quantitative Urinary protein in 24 hours;

Secondary ID(s)

Source(s) of Monetary Support

Self-financed

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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