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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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18 April 2017 |
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Main ID: |
ChiCTR-ONRC-11001846 |
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Date of registration:
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2011-12-28 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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The research of immue state and current treatment in Ankylosing spondylitis
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Scientific title:
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The research of immue state and current treatment in Ankylosing spondylitis |
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Date of first enrolment:
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2009-12-03 |
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Target sample size:
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Traditional therapy group:500;biological agent group:500;thalidomide group:500; |
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Recruitment status: |
Completed |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=7701 |
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Study type:
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Observational study |
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Study design:
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Non randomized control
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Phase:
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Pilot study
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Contacts
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Name:
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Ping Zhu
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Address:
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15 West Changle Road, Xi'an, Shaanxi, China
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Telephone:
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+86 029 84771581 |
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Email:
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zhuping@fmmu.edu.cn |
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Affiliation:
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Name:
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Qing Han
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Address:
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15 West Changle Road, Xi'an, Shaanxi, China
710032
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Telephone:
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+86 13572821171 |
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Email:
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13572821171@139.com |
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Affiliation:
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Department of Clinical Immunology, Xijing Hospital,Fouth MilitaryMedical University |
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. patients hadto meet the modified New York clinical criteria in 1984 for definite Ankylosing spondylitis;
2. patients can provid the informed consent document in writting, and agree to abide by the requirement for the research plan.
Exclusion criteria: 1. Female patients who are pregnant or breastfeeding;
2. patients who have severe systemic diaease; no perceptibility or can not take care of onself in daily life;malignant tumor.
Age minimum:
18
Age maximum:
65
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Ankylosing spondylitis
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Intervention(s)
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Traditional therapy group:DMARDs;biological agent group:biological agent;thalidomide group:thalidomide;
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Primary Outcome(s)
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TH1 cell quantity;Treg cell quantity;TH17 cell quantity;the level of associated cytokine;expression of assocoated Transcription factors;ASDAS;BASDAI;BASFI;BASMI;Harris score;radiology;magnetic resonance imaging;CRP;ESR;
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Source(s) of Monetary Support
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Xijing Hospital, Fourth Military Medical University
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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