WHO Model Prescribing Information: Drugs Used in Skin Diseases
(1997; 132 pages) [French] [Spanish] Voir le document au format PDF
Table des matières
Afficher le documentPreface
Afficher le documentIntroduction
Ouvrir ce répertoire et afficher son contenuParasitic infections
Ouvrir ce répertoire et afficher son contenuInsect and arachnid bites and stings
Ouvrir ce répertoire et afficher son contenuSuperficial fungal infections
Ouvrir ce répertoire et afficher son contenuSubcutaneous fungal infections
Ouvrir ce répertoire et afficher son contenuBacterial infections
Ouvrir ce répertoire et afficher son contenuViral infections
Ouvrir ce répertoire et afficher son contenuEczematous diseases
Ouvrir ce répertoire et afficher son contenuScaling diseases
Ouvrir ce répertoire et afficher son contenuPapulosquamous diseases
Afficher le documentCutaneous reactions to drugs
Ouvrir ce répertoire et afficher son contenuPigmentary disorders
Ouvrir ce répertoire et afficher son contenuPremalignant lesions and malignant tumours
Fermer ce répertoirePhotodermatoses
Afficher le documentSolar urticaria
Afficher le documentPolymorphous light eruptions
Afficher le documentActinic prurigo
Afficher le documentChemical photodermatoses
Ouvrir ce répertoire et afficher son contenuBullous dermatoses
Afficher le documentAlopecia areata
Afficher le documentUrticaria
Ouvrir ce répertoire et afficher son contenuConditions common in children
Afficher le documentAcne vulgaris
Afficher le documentPruritus
Afficher le documentTropical ulcers
Ouvrir ce répertoire et afficher son contenuAntimicrobial drugs
Ouvrir ce répertoire et afficher son contenuAntifugal drugs
Ouvrir ce répertoire et afficher son contenuAntiseptic agents
Ouvrir ce répertoire et afficher son contenuKeratoplastic and keratolytic agents
Ouvrir ce répertoire et afficher son contenuScabicides and pediculicides
Ouvrir ce répertoire et afficher son contenuAnti-inflammatory and antipruritic drugs1
Ouvrir ce répertoire et afficher son contenuAntiallergics and drugs used in anaphylaxis
Ouvrir ce répertoire et afficher son contenuUltraviolet radiation-blocking agents (sunscreens)
Ouvrir ce répertoire et afficher son contenuMiscellaneous drugs
Ouvrir ce répertoire et afficher son contenuAnnex
Afficher le documentSelected WHO Publications of Related Interest
Afficher le documentBack cover
 

Actinic prurigo

Actinic prurigo, which occurs particularly among people of American Indian and Asian descent, first appears during childhood. It usually regresses completely during adolescence and early adulthood but can persist longer. Recurrent patchy oedematous erythema results in the formation of persistent excoriated plaques, papules and nodules. Cheilitis is common, particularly during the early phases of the disease. Vesicles and small pitted scars sometimes develop on the face, while chronic conjunctivitis and pterygium formation are common among affected children in South America, New Mexico and Saskatchewan, Canada.

Treatment

Sunscreens, when used regularly, provide some protection. The cutaneous signs are suppressed by thalidomide and, to a lesser extent, topical corticosteroids, but they recur within a few weeks of discontinuation of treatment. Thalidomide should be avoided in women of child-bearing age, since it is a proven teratogen. If this is not possible, it is imperative that pregnancy be excluded before this treatment is instituted. Effective contraception must be used during the 4 weeks preceding and following treatment, as well as during the treatment period. Should pregnancy occur despite these precautions, there is a high risk of severe malformation of the fetus.

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