Determinants of Antimicrobial Use in the Developing World
(2002; 39 pages)


Antibiotics play a key role in treating diseases of bacterial origin, a major cause of morbidity and mortality in the developing world. High levels of consumption, often clinically unnecessary, have led to a steady increase in drug resistance, particularly to antibiotics used in treating high prevalence diseases. The effectiveness of many antibiotics is lost almost as quickly as scientists discover them. This review provides information from well-designed scientific studies on the factors that influence the use of antibiotics by health providers, dispensers and community members in non-industrialized countries. These practices tend to be determined by a complex and multi-layered mix of medical, psychosocial, cultural, economic, and political factors. Understanding these factors can lead to the development of more effective policies and programs to address inappropriate antibiotic use...

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