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Drug and Therapeutics Committees - A Practical Guide
(2003; 155 pages) [French] [Spanish] [Vietnamese] Ver el documento en el formato PDF
Irrational use of medicines is a widespread problem at all levels of health care, but especially in hospitals. This is particularly worrying as resources are generally scarce and prescribers in communities often copy hospital prescribing practices. Use of medicines can be greatly improved and wastage reduced if some simple principles of drug management are followed. But it is difficult to implement these principles because staff from many different disciplines are involved, often with no forum for bringing them together to develop and implement appropriate medicines policies. A drug and therapeutics committee (DTC) provides such a forum, allowing all the relevant people to work together to improve health care delivery, whether in hospitals or other health facilities. In many developed countries a well functioning DTC has been shown to be very effective in addressing drug use problems. However, in many developing countries DTCs do not exist and in others they do not function optimally, often due to lack of local expertise or a lack of incentives. Drug and Therapeutics Committees: A Practical Guide provides guidance to doctors, pharmacists, hospital managers and other professionals who may be serving on DTCs and/or who are concerned with how to improve the quality and cost efficiency of therapeutic care. It is relevant for all kinds of DTCs - whether in public or private hospitals and whether at district or tertiary referral level. This comprehensive manual covers a committee’s functions and structure, the medicines formulary process, and how to assess new medicines. The chapters on tools to investigate drug use and strategies to promote rational use are followed by a discussion of antimicrobial resistance and infection control. The publication concludes by explaining in detail how to start a committee or improve the effectiveness of an existing one. The manual has been developed by the WHO Department of Essential Drugs and Medicines Policy, in collaboration with the Rational Pharmaceutical Management Plus Program of Management Sciences for Health.
Índice de contenido
Ver el documentoAcronyms and abbreviations
Ver el documentoPreface
Abrir esta carpeta y ver su contenido1. Introduction
Abrir esta carpeta y ver su contenido2.Structure and organization of a drug and therapeutics committee
Abrir esta carpeta y ver su contenido3. Managing the formulary process
Abrir esta carpeta y ver su contenido4.Assessing new medicines
Abrir esta carpeta y ver su contenido5.Ensuring medicine safety and quality
Abrir esta carpeta y ver su contenido6.Tools to investigate the use of medicines
Abrir esta carpeta y ver su contenido7.Promoting the rational use of medicines
Abrir esta carpeta y ver su contenido8.Antimicrobials and injections
Abrir esta carpeta y ver su contenido9. Getting started
Ver el documentoGlossary1
Ver el documentoReferences
Ver el documentoFurther reading
Ver el documentoUseful addresses and websites
Ver el documentoBack cover

Drug and Therapeutics Committees - A Practical Guide


World Health Organization
Department of Essential Drugs and Medicines Policy
Geneva, Switzerland

In collaboration with

Management Sciences for Health
Center for Pharmaceutical Management
Rational Pharmaceutical Management Program
Arlington, Virginia, USA


Kathleen Holloway1 (Editor)
Terry Green2

with contributions from: Edelisa Carandang,1 Hans Hogerzeil,1 Richard Laing,3 David Lee,2

The text was reviewed by: John Chalker,2 Mary Couper,1 Andrew Creese,1 Marthe Everard,1 Anna Paula di Felici,4 Chris Forshaw,5 David Henry,6 Yvan Hutin,7 Sabine Kopp,1 Souly Phanouvong,8 Clive Ondari,1 Lembit Rago,1 Marcus Reidenberg,9 Budiono Santoso,10 Anthony Savelli2 and Rosamund Williams.4

1 Department of Essential Drugs and Medicines Policy (EDM), World Health Organization, Geneva, Switzerland

2 Management Sciences for Health (MSH), Washington DC, USA*

3 Department of International Health, Boston University, Boston, Massachusetts, USA

4 Department of Communicable Disease Surveillance and Response, World Health Organization, Geneva, Switzerland

5 Uganda Health Sector Programme Support, Danida, Kampala, Uganda

6 Department of Clinical Pharmacology, University of Newcastle, New South Wales, Australia

7 Safe Injection Global Network, Department of Blood Safety and Clinical Technology, World Health Organization, Geneva, Switzerland

8 Global Assistance Initiatives, United States Pharmacopeia, Maryland, USA

9 Division of Clinical Pharmacology, Weill Medical College of Cornell University, New York, USA

10 Regional Office for the Western Pacific, World Health Organization, Manila, the Philippines

* The MSH Rational Pharmaceutical Management Plus Program is supported by the U.S. Agency for International Development, under the terms of cooperative agreement number HRN-A-00-00-00016-00.

© World Health Organization 2003

All rights reserved.

The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement.

The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.

The World Health Organization does not warrant that the information contained in this publication is complete and correct and shall not be liable for any damages incurred as a result of its use.

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