WHO Model Prescribing Information: Drugs Used in Skin Diseases
(1997; 132 pages) [French] [Spanish] Ver el documento en el formato PDF
Índice de contenido
Ver el documentoPreface
Ver el documentoIntroduction
Abrir esta carpeta y ver su contenidoParasitic infections
Abrir esta carpeta y ver su contenidoInsect and arachnid bites and stings
Abrir esta carpeta y ver su contenidoSuperficial fungal infections
Abrir esta carpeta y ver su contenidoSubcutaneous fungal infections
Abrir esta carpeta y ver su contenidoBacterial infections
Abrir esta carpeta y ver su contenidoViral infections
Abrir esta carpeta y ver su contenidoEczematous diseases
Abrir esta carpeta y ver su contenidoScaling diseases
Abrir esta carpeta y ver su contenidoPapulosquamous diseases
Ver el documentoCutaneous reactions to drugs
Abrir esta carpeta y ver su contenidoPigmentary disorders
Abrir esta carpeta y ver su contenidoPremalignant lesions and malignant tumours
Abrir esta carpeta y ver su contenidoPhotodermatoses
Abrir esta carpeta y ver su contenidoBullous dermatoses
Ver el documentoAlopecia areata
Ver el documentoUrticaria
Abrir esta carpeta y ver su contenidoConditions common in children
Ver el documentoAcne vulgaris
Ver el documentoPruritus
Ver el documentoTropical ulcers
Abrir esta carpeta y ver su contenidoAntimicrobial drugs
Abrir esta carpeta y ver su contenidoAntifugal drugs
Abrir esta carpeta y ver su contenidoAntiseptic agents
Cerrar esta carpetaKeratoplastic and keratolytic agents
Ver el documentoBenzoyl peroxide
Ver el documentoCoal tar
Ver el documentoDithranol
Ver el documentoSalicylic acid
Ver el documentoTretinoin
Abrir esta carpeta y ver su contenidoScabicides and pediculicides
Abrir esta carpeta y ver su contenidoAnti-inflammatory and antipruritic drugs1
Abrir esta carpeta y ver su contenidoAntiallergics and drugs used in anaphylaxis
Abrir esta carpeta y ver su contenidoUltraviolet radiation-blocking agents (sunscreens)
Abrir esta carpeta y ver su contenidoMiscellaneous drugs
Abrir esta carpeta y ver su contenidoAnnex
Ver el documentoSelected WHO Publications of Related Interest
Ver el documentoBack cover
 

Coal tar

Solution, 5-10%
Ointment (crude coal tar), 1%

General information

Coal tar is a keratolytic agent that inhibits excessive proliferation of epidermal cells by reducing DNA synthesis and mitotic activity to normal levels.

Coal tar is not significantly absorbed following topical application.

Clinical information

Uses

Treatment of chronic psoriasis, either alone or in combination with exposure to ultraviolet light.

Dosage and administration

Adults and children: 100 ml of solution should be thoroughly mixed with bath water and the patient should soak for 10-20 minutes. Treatment may be repeated daily until the lesions have resolved.

Alternatively, a thin layer of ointment is applied to the affected areas once daily until the lesions have resolved.

Phototherapy should not be started until at least 24 hours after treatment and until all traces of the coal tar preparation have been removed from the skin.

Contraindications

Known hypersensitivity to tar preparations.

Precautions

Coal tar preparations should not be applied to inflamed, broken or infected skin.

Exposure to direct sunlight should be avoided as far as possible for at least 24 hours after treatment, because of the risk of photosensitivity reactions.

Although coal tar is a potential carcinogen, there is no evidence that it increases the risk of skin cancer at the doses used therapeutically.

Use in pregnancy

Safe use in pregnancy has not been demonstrated. Treatment should be deferred until after delivery whenever possible.

Adverse effects

Coal tar preparations cause skin irritation. Rarely, allergic sensitization occurs.

Photosensitivity reactions may occur, particularly when other photosensitizing agents are used.

Patients should be warned that staining of the skin and hair may occur.

Storage

Preparations should be stored in tightly closed containers, protected from light. They should not be allowed to freeze.

Ir a la sección anterior
Ir a la siguiente sección
 
 
El Portal de Información - Medicamentos Esenciales y Productos de Salud de la OMS fue diseñado y es mantenido por la ONG Human Info. Última actualización: le 1 diciembre 2019