WHO Model Prescribing Information: Drugs Used in Skin Diseases
(1997; 132 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentPreface
View the documentIntroduction
Open this folder and view contentsParasitic infections
Open this folder and view contentsInsect and arachnid bites and stings
Open this folder and view contentsSuperficial fungal infections
Close this folderSubcutaneous fungal infections
View the documentSporotrichosis
View the documentMycetoma
View the documentChromomycosis
View the documentSubcutaneous zygomycosis
Open this folder and view contentsBacterial infections
Open this folder and view contentsViral infections
Open this folder and view contentsEczematous diseases
Open this folder and view contentsScaling diseases
Open this folder and view contentsPapulosquamous diseases
View the documentCutaneous reactions to drugs
Open this folder and view contentsPigmentary disorders
Open this folder and view contentsPremalignant lesions and malignant tumours
Open this folder and view contentsPhotodermatoses
Open this folder and view contentsBullous dermatoses
View the documentAlopecia areata
View the documentUrticaria
Open this folder and view contentsConditions common in children
View the documentAcne vulgaris
View the documentPruritus
View the documentTropical ulcers
Open this folder and view contentsAntimicrobial drugs
Open this folder and view contentsAntifugal drugs
Open this folder and view contentsAntiseptic agents
Open this folder and view contentsKeratoplastic and keratolytic agents
Open this folder and view contentsScabicides and pediculicides
Open this folder and view contentsAnti-inflammatory and antipruritic drugs1
Open this folder and view contentsAntiallergics and drugs used in anaphylaxis
Open this folder and view contentsUltraviolet radiation-blocking agents (sunscreens)
Open this folder and view contentsMiscellaneous drugs
Open this folder and view contentsAnnex
View the documentSelected WHO Publications of Related Interest
View the documentBack cover
 

Sporotrichosis

Cutaneous sporotrichosis, which is caused by Sporothrix schenckii, presents as a nodular or pustular lesion which later ulcerates to form a chancre. After several weeks or months multiple painless subcutaneous nodules appear, indicating that lymphatic involvement has occurred.

Treatment

The infection is usually cured by oral treatment with a saturated solution of potassium iodide (1 g/ml). Treatment should be started with a dosage of five drops three times daily and increased by one drop per dose up to a maximum of 30-40 drops three times daily. The drug should be diluted in a glass of fruit juice, milk or water, or taken with food to minimize gastrointestinal side-effects. Treatment should be continued for at least 1 month after all signs have resolved. If signs of iodism occur (e.g. nausea, vomiting, coryza and an acneiform rash) treatment should be temporarily suspended and restarted several days later at lower dosage. Patients who are unable to tolerate potassium iodide should receive itraconazole, 200-400 mg daily.

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