WHO Model Prescribing Information: Drugs Used in Skin Diseases
(1997; 132 pages) [French] [Spanish] View the PDF document
Table of Contents
View the documentPreface
View the documentIntroduction
Open this folder and view contentsParasitic infections
Open this folder and view contentsInsect and arachnid bites and stings
Open this folder and view contentsSuperficial fungal infections
Open this folder and view contentsSubcutaneous fungal infections
Open this folder and view contentsBacterial infections
Open this folder and view contentsViral infections
Open this folder and view contentsEczematous diseases
Open this folder and view contentsScaling diseases
Open this folder and view contentsPapulosquamous diseases
View the documentCutaneous reactions to drugs
Open this folder and view contentsPigmentary disorders
Open this folder and view contentsPremalignant lesions and malignant tumours
Open this folder and view contentsPhotodermatoses
Open this folder and view contentsBullous dermatoses
View the documentAlopecia areata
View the documentUrticaria
Open this folder and view contentsConditions common in children
View the documentAcne vulgaris
View the documentPruritus
View the documentTropical ulcers
Open this folder and view contentsAntimicrobial drugs
Close this folderAntifugal drugs
View the documentAmphotericin B
View the documentBenzoic acid + salicylic acid (Whitfield’s ointment)
View the documentClotrimazole
View the documentEconazole
View the documentFluconazole
View the documentFlucytosine
View the documentGriseofulvin
View the documentItraconazole
View the documentKetoconazole
View the documentMiconazole
View the documentNystatin
View the documentPotassium iodide
View the documentSelenium sulfide
View the documentSodium thiosulfate
View the documentTerbinafine
Open this folder and view contentsAntiseptic agents
Open this folder and view contentsKeratoplastic and keratolytic agents
Open this folder and view contentsScabicides and pediculicides
Open this folder and view contentsAnti-inflammatory and antipruritic drugs1
Open this folder and view contentsAntiallergics and drugs used in anaphylaxis
Open this folder and view contentsUltraviolet radiation-blocking agents (sunscreens)
Open this folder and view contentsMiscellaneous drugs
Open this folder and view contentsAnnex
View the documentSelected WHO Publications of Related Interest
View the documentBack cover
 

Nystatin

Pessary, 100000 IU
Oral suspension, 100000 IU/ml
Ointment or cream, 100000 IU/g

General information

Nystatin is an antifungal polyene antibiotic derived from Streptomyces noursei. It is effective against infections caused by a wide range of yeasts and yeast-like fungi.

Clinical information

Uses

Treatment of oral, vaginal and cutaneous candidosis.

Dosage and administration

All doses are suitable for adults and children.

Oral candidosis:

1-2 ml of suspension four times daily.

Vaginal candidosis:

100 000 IU as pessaries or 100 000 IU (1g) of cream inserted high into the vagina nightly for at least 2 weeks.

Cutaneous candidosis:

A thin layer of cream or ointment should be applied to all affected areas twice daily for 2 weeks.

In the above diseases, treatment should be continued for at least 48 hours after clinical cure. Higher doses and a longer period of treatment may be necessary in immunocompromised patients.

Contraindications and precautions

Treatment should be discontinued if symptoms of irritation or sensitization occur.

Use in pregnancy

Safe use in pregnancy has not been established. The need for treatment must be determined by the condition of the mother.

Adverse effects

Mild and transient nausea, vomiting and diarrhoea may occur after oral administration. Irritation rarely occurs after topical application.

Storage

Nystatin ointment and cream should be stored in well-closed containers. Pessaries and oral suspension should be stored below 15 °C in well-closed containers, protected from light.

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