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dc.contributor.authorJoint FAO/WHO Expert Committee on Food Additivesen
dc.contributor.authorWorld Health Organizationen
dc.contributor.authorFood and Agriculture Organization of the United Nationsen
dc.coverage.spatialGeneva
dc.date.accessioned2012-06-16T13:45:17Z
dc.date.available2012-06-16T13:45:17Z
dc.date.created1993en
dc.date.issued1993en
dc.identifier.isbn9241208376
dc.identifier.urihttps://iris.who.int/handle/10665/36981
dc.description53 p.en
dc.description.abstractPresents the conclusions of an expert committee commissioned to evaluate the safety for human consumption of selected food additives and contaminants and to establish acceptable daily intakes for these substances. The committee also establishes specifications for the identity and purity of food additives in order to make certain that the materials subjected to toxicological testing are adequately defined and correspond to the products in commerce. The report, which has two main parts, considers the acceptable daily intakes for 23 food additives and four contaminants. Sections in the first part address various methodological problems concerning the principles of safety assessment. Issues discussed include the possibility that the administration of test substances by corn oil gavage may have an independent effect on the incidence of certain tumours, and principles governing the formulation of specifications for enzyme preparations from genetically modified organisms, for heavy metals, and for substances derived from natural sources. The second and most extensive part provides succinct summaries of the toxicological data examined and factors considered when evaluating each substance and allocating an acceptable daily intake. A particularly detailed assessment of the toxicological hazards to humans of saccharin is included. The report also evaluates safety data on cadmium, 3-chloro-1,2-propanediol, 1,3-dichloro-2-propanol, and lead. For lead, the provisional tolerable weekly intake (‎PTWI)‎ for adults was withdrawn and the existing PTWI for infants and children was reconfirmed and extended to all age groupsen
dc.language.isoesen
dc.language.isoenen
dc.language.isofren
dc.language.isoruen
dc.publisherWorld Health Organization
dc.publisherWorld Health Organization
dc.relation.ispartofseriesWHO technical report series ; 837en
dc.subject.meshFood Additivesen
dc.subject.meshFood Contaminationen
dc.subject.otherNutrition and Food Safetyen
dc.titleEvaluation of certain food additives and contaminants : forty-first report of the Joint FAO/WHO Expert Committee on Food Additives [‎meeting held in Geneva from 9 to 18 February 1993]‎en
dc.title.alternativeEvaluación de ciertos aditivos alimentarios y contaminantes de los alimentos : 41 informe del Comité Mixto FAO/OMS de Expertos en Aditivos Alimentarios [‎se reunió en Ginebra del 9 al 18 de febrero de 1993]‎en
dc.title.alternativeEvaluation de certains additifs alimentaires et contaminants : quarante et unième rapport du Comité mixte FAO/OMS d'experts des additifs alimentaires [‎réuni à Genève du 9 au 18 février 1993]‎en
dc.subject.meshqualifiertoxicityen
dc.relation.isnodouble39996*


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