Dengue in Brazil during 1999–2009: a review.

Abstract

Over the period 1999 through 2009, the incidence of dengue in Brazil has shown an upward trend with more than 700 000 cases per year reported during 2002 and 2008. Despite efforts to control Aedes aegypti, a hyper-endemic situation has remained with large outbreaks involving all the four dengue serotypes (‎DENV-1 to 4)‎. The average age of DHF/DSS cases has decreased, making it a disease affecting children. The number of fatalities has also increased. While other countries in the Americas have also witnessed an upward trend in case numbers, Brazil has been subject to more extreme peaks. Other arboviruses also cause sporadic human cases which are commonly confused with dengue and remain undiagnosed.