Browsing Dengue Bulletin by Title
Now showing items 1-20 of 534
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A clinical, epidemiology and virological study of a dengue fever outbreak in Guangzhou, China-2002-2006.
(2007)We analysed the clinical and epidemiological characteristics of dengue fever (DF) during the dengue virus (DENV)-1 outbreak in Guangzhou, China. Clinical and epidemiological data of 1342 patients with DF from May 2002 to November 2006 were analyzed retrospectively. The average age was 34.7±13.2 years. The ratio of male to female was 1.05:1. The peak time of the epidemic lasted from August to October. The most common manifestations included fever (100%), headache (85.9%), myalgia (64.5%), bone soreness (46.6%), fatigue (78.2%), skin rash (65.9%) ... -
A guide to DHF/DSS management - the Singapore experience.
(2001-12)A guide to the medical management of dengue for reducing its case-fatality rate as experienced in Singapore is furnished. The mortality from dengue in Singapore is low and most cases recover uneventfully. However, complacency and under-estimation of the disease does occur. It is important to recognize the symptoms of severity and understand the patho-physiology that leads to dengue shock syndrome (DSS). A protocol giving indications of platelet transfusion will guide appropriate usage. Patients should be informed prior to platelet transfusion as ... -
A guide to DHF/DSS management - the Singapore experience.
(2001-12)A guide to the medical management of dengue for reducing its case-fatality rate as experienced in Singapore is furnished. The mortality from dengue in Singapore is low and most cases recover uneventfully. However, complacency and under-estimation of the disease does occur. It is important to recognize the symptoms of severity and understand the patho-physiology that leads to dengue shock syndrome (DSS). A protocol giving indications of platelet transfusion will guide appropriate usage. Patients should be informed prior to platelet transfusion as ... -
A hypothetical intervention to reduce plasma leakage in dengue haemorrhagic fever.
(2011-12)Plasma leakage from increased vascular permeability, if left unattended, will lead to intravascular volume depletion. The ensuing tissue hypoperfusion and the consequent life-threatening complications may have a fatal outcome in dengue haemorrhagic fever (DHF). Although an accurately calculated volume of fluid infused during the critical phase of plasma leakage can prevent such an eventuality, the practical difficulties in its execution with properly-timed adjustments to the fluid infusion rate and the aggressive monitoring needed during this ... -
A new approach to classify risk in dengue infection using bioelectrical impedance analysis.
(2007)The study on risk classification was conducted on 183 hospitalized dengue patients (4 DF, 179 DHF). The severity of the risk criteria was determined based on three blood investigations, namely, platelet (PLT) count (less than or equal to 30 000 cells per mm3), haematocrit (HCT) (increase by more than or equal to 20%), and either aspartate aminotransferase (AST) level (raised by 5-fold the normal upper limit) or alanine aminotransferase (ALT) level (raised by 5-fold the normal upper limit). The patients were divided into three groups based on their ... -
A new tool for the diagnosis and molecular surveillance of dengue infections in clinical samples.
(2004-12)Dengue fever and dengue haemorrhagic fever are amongst the most important challenges in tropical diseases due to their expanding geographical distribution, increasing outbreak frequency, hyperendemicity and evolution of virulence. Here, the use of a RT-nested PCR for both the diagnosis and genetic characterization of dengue infections in clinical samples is described. -
A novel method of controlling a dengue mosquito vector, Aedes aegypti (Diptera: Culicidae) using an aquatic mosquito predator, Diplonychus indicus (Hemiptera: Belostomatidae) in tyres
(2009-12)An investigation was undertaken to evaluate the biocontrol potential of a mosquito predator, Diplonychus indicus, against the immatures of dengue vectors breeding in used tyres. Two gardens were selected and ten tyres each filled with water were kept in different sites of both gardens. One was considered as “control” where no predator was used, whereas in the tyres kept in the “experimental” garden, two second instars of D. indicus were released into each tyre. The absolute density of larvae, pupae and man-landing rate of dengue vector were ... -
A private hospital-based study assessing knowledge, attitudes, practices and costs associated with dengue illness in Surat, India.
(2010-12)We conducted a descriptive cross-sectional study at a private children’s and general hospital in Surat,India, during the 2006 dengue season (June to December 2006). We examined knowledge, attitudes and practices of patients associated with dengue and estimated the cost of a dengue episode for the study sample. Of 62 patients with suspected dengue, 40 consented to participate in this study. We interviewed 27 retrospectively in their homes and 13 prospectively during their hospitalization. Among the respondents, 75% were male, 85% were under the ... -
Acknowledgements.
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Acute abdominal pain in dengue haemorrhagic fever: A study in Sri Lanka, 2009.
(2009-12)We attempted to unravel the association of acute severe abdominal pain in 14 patients with dengue haemorrhagic fever during the epidemic in 2009. All had secondary dengue infection. The findings were severe thrombocytopenia (the mean platelet count 18x109/l, range 12–48), high liver enzymes (mean ALT 374U/l, range 82–2692), ascites in all cases, acute hepatitis in 11 cases (79%), acalculous cholecystitis in five cases (42%), and renal involvement in three cases (25%). All had normal serum amylase level and normal-looking pancreas in ultrasound ...
