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Gastric mucosal function in portal hypertensive gastropathy secondary to schistosomal hepatic fibrosis: effect of sclerotherapy

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Abstract
Gastric mucosal function in portal hypertensive gastropathy secondary to schistosomal hepatic fibrosis [‎SHF]‎ was evaluated. Group I comprised 20 patients with no bleeding; 10 had portal hypertensive gastropathy [‎PHG]‎. Group II comprised 20 patients with bleeding. Free acidity, total acidity, basal acid output, serum pepsinogen I, gastric mucosal blood flow [‎GMBF]‎ and gastrin were significantly lower in group II, whereas serum gastrin and somatostatin staining were significantly higher. No histopathological changes were noted between both groups, In conclusion, bleeding caused by SHF results in hypoacidity, hypergastrinaemia and hypopepsinogenaemia. Estimated GMBF distinguishes patients with PHG and those who are bleeders
Citation
El Deeb, S. (‎1996)‎. Gastric mucosal function in portal hypertensive gastropathy secondary to schistosomal hepatic fibrosis: effect of sclerotherapy. EMHJ - Eastern Mediterranean Health Journal, 2 (‎3)‎, 470-481, 1996 https://apps.who.int/iris/handle/10665/119461
Journal
EMHJ - Eastern Mediterranean Health Journal, 2 (‎3)‎, 470-481, 1996
Description
470-481
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/0203/emhj_1996_2_3_470_481.pdf
Language
English
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  • EMRO Journal Articles (‎EMHJ)‎
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