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Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan

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Abstract
A latex agglutination test to detect urinary antigens for visceral leishmaniasis [‎VL]‎ was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all KAtex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While KAtex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test [‎DAT]‎ was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results
Citation
El Safi, S.H., Abdel Haleem, A., Hammad, A., El Basha, I., Omer, A. et al. (‎2003)‎. Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan. EMHJ - Eastern Mediterranean Health Journal, 9 (‎4)‎, 844-855, 2003 https://apps.who.int/iris/handle/10665/119338
Journal
EMHJ - Eastern Mediterranean Health Journal, 9 (‎4)‎, 844-855, 2003
Description
844-855
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/0904/9_4_2003_844_855.pdf
Language
English
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