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dc.contributor.authorAbou Jabal, A.
dc.contributor.authorShubeilat, T.
dc.contributor.authorHajjiri, F.
dc.date.accessioned2014-06-17T11:24:43Z
dc.date.available2014-06-17T11:24:43Z
dc.date.issued2003EN
dc.identifier.issn1020-3397EN
dc.identifier.otherhttp://applications.emro.who.int/emhj/0903/emhj_2003_9_3_407_412.pdfEN
dc.identifier.urihttps://apps.who.int/iris/handle/10665/119291
dc.description407-412EN
dc.description.abstractThe study aimed to determine the specificity and sensitivity of the Ortho BioVue two-column agglutination system for the detection of low concentrations of clinically significant antibodies in serum. The BioVue system was compared with the conventional tube technique [‎LISS-Coombs indirect antiglobulin test]‎, and the two-stage Papenzyme test was used to resolve discrepancies between the two methods. We tested 3000 serum samples from randomly selected patients at King Hussein Medical Centre. Both the antibody screening and identification gave negative results in 2952 patients and positive results in 48 patients. We found the BioVue system to be the more sensitive technique. However, if papain enzyme-treated cells were included in the conventional tube technique when applied to antibody screening and identification, both methods would be of comparable sensitivityEN
dc.language.isoenEN
dc.subjectCase-Control StudiesEN
dc.subjectCost-Benefit AnalysisEN
dc.subjectHemagglutination TestsEN
dc.subjectIsoantibodiesEN
dc.subjectMass ScreeningEN
dc.subjectPapainEN
dc.subjectRho[‎D]‎ Immune GlobulinEN
dc.subjectSensitivity and SpecificityEN
dc.subject.meshAntibodiesEN
dc.titleEvaluation of 2-column agglutination versus conventional tube technique for antibody screeningEN
dc.relation.ispartofjournalEMHJ - Eastern Mediterranean Health Journal, 9 (‎3)‎, 407-412, 2003


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