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Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children

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Abstract
We evaluated the ability of serum transferrin receptor [‎sTFR]‎ to identify different types of anaemia in children. Thus 150 Egyptian children suffering from anaemia [‎iron deficiency anaemia, anaemia of chronic disease and beta-thalassaemia]‎ were enrolled, together with 50 controls. There was a significant increase in the mean levels of sTFR in the groups with iron deficiency anaemia and thalassaemia, and a significant decrease in mean sTFR levels in the group with anaemia of chronic disease. Serum ferritin levels were significantly higher in all patient groups except the group with iron deficiency anaemia. There were also significant correlations between the sTFR and sTFR/log ferritin ratio [‎sTFR-F index]‎ and different indices of iron status and of erythropoiesis. The sTFR-F index could be used as a diagnostic or screening tool for iron deficiency anaemia, anaemia of chronic disease and thalassaemia
Citation
Ragab, L., Ibrahim, H.A., Eid, A.S., Kotb, T. & Konsowa, M.F. (‎2002)‎. Suitability of soluble transferrin receptor for the clinical diagnosis of different types of anaemia in children. EMHJ - Eastern Mediterranean Health Journal, 8 (‎2-3)‎, 298-307, 2002 https://apps.who.int/iris/handle/10665/119165
Journal
EMHJ - Eastern Mediterranean Health Journal, 8 (‎2-3)‎, 298-307, 2002
Description
298-307
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/0802_3/emhj_2002_8_2_3_298_307.pdf
Language
English
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