Show simple item record

dc.contributorEl Bindary, E.M.EN
dc.contributorDarwish, A.Z.EN
dc.date.accessioned2014-06-17T11:06:32Z
dc.date.available2014-06-17T11:06:32Z
dc.date.issued2001EN
dc.identifier.issn1020-3397EN
dc.identifier.otherhttp://applications.emro.who.int/emhj/0704_5/EMHJ_2001_7_4-5_697_706.pdfEN
dc.identifier.urihttp://www.who.int/iris/handle/10665/119077
dc.description697-706EN
dc.description.abstractWe investigated the plasma levels of tumour necrosis factor-alpha [‎TNF-alpha]‎, leptin and insulin, and their relation to body mass index [‎BMI]‎ in 80 male patients who presented with chronic heart failure [‎mean age: 47 +/- 4 years]‎ at Tanta University Hospital. Plasma leptin, TNF-alpha and insulin were significantly increased and BMI significantly decreased in New York Heart Association classes III and IV patients. TNF-alpha, leptin and insulin were positively correlated, and TNF-alpha and BMI and leptin and BMI were negatively correlated in stages III and IV of heart failure. We conclude that cytokine neuroendocrine activation may form part of advanced stage heart failure. It may also be responsible for worsening cachexia, and can be used as a marker to determine disease severityEN
dc.language.isoenEN
dc.subjectBody Mass IndexEN
dc.subjectCachexiaEN
dc.subjectCase-Control StudiesEN
dc.subjectChronic DiseaseEN
dc.subjectHeart FailureEN
dc.subjectHyperinsulinismEN
dc.subjectImmunoenzyme TechniquesEN
dc.subjectInsulinEN
dc.subjectLeptinEN
dc.subjectNeurosecretory SystemsEN
dc.subjectPulmonary Wedge PressureEN
dc.subjectRadioimmunoassayEN
dc.subject.meshBiological MarkersEN
dc.titleNew biochemical markers in chronic heart failureEN
dc.relation.ispartofjournalEMHJ - Eastern Mediterranean Health Journal, 7 (‎4-5)‎, 697-706, 2001


Files in this item

Thumbnail

This item appears in the following Collection(‎s)‎

Show simple item record