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dc.contributor.authorEl Hazmi, M.A.
dc.contributor.authorWarsy, A.S.
dc.date.accessioned2014-06-17T10:42:41Z
dc.date.available2014-06-17T10:42:41Z
dc.date.issued1999EN
dc.identifier.issn1020-3397EN
dc.identifier.otherhttp://applications.emro.who.int/emhj/0506/EMHJ_1999_5_6_1183_1187.pdfEN
dc.identifier.urihttps://apps.who.int/iris/handle/10665/118815
dc.description1183-1187EN
dc.description.abstractOur studies of the Saudi population have shown that in patients with mild presentation of sickle-cell disease [‎SCD]‎ from Saudi Arabia's eastern region, the prevalence of polymorphic sites is high. However, the prevalence is very low in patients with severe SCD from the south-west of the country. We expanded these studies to a group of Yemeni patients with severe SCD, resident in Riyadh. We investigated a total of 60 chromosomes carrying the sickle-cell [‎Hb S]‎ gene and 14 chromosomes carrying the Hb A gene. Amongst the Hb AA group, the prevalence was 42.9% and 57.1% for the presence [‎+]‎ and absence [‎-]‎ of Xmn I polymorphic sites. In the Hb SS individuals, the prevalence of Xmn I polymorphic sites was similar to the prevalence reported in the south-western region of Saudi ArabiaEN
dc.language.isoenEN
dc.subjectCase-Control StudiesEN
dc.subjectDeoxyribonucleases, Type II Site-SpecificEN
dc.subjectErythrocyte CountEN
dc.subjectErythrocyte IndicesEN
dc.subjectGlobinsEN
dc.subjectHemoglobin AEN
dc.subjectHemoglobin, SickleEN
dc.subjectPolymorphism, GeneticEN
dc.subjectSeverity of Illness IndexEN
dc.subject.meshAnemia, Sickle CellEN
dc.titleMolecular studies on Yemeni sickle-cell-disease patients: Xmn I polymorphismEN
dc.relation.ispartofjournalEMHJ - Eastern Mediterranean Health Journal, 5 (‎6)‎, 1183-1187, 1999


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