Triclabendazole in the treatment of human fascioliasis: a community-based study
AbstractThe efficacy of triclabendazole in the treatment of chronic Fasciola infection was assessed. A total of 134 asymptomatic cases of established Fasciola infection were treated: 68 individuals received a single dose of 10 mg/kg and 66 individuals received 2 doses of 10 mg/kg on 2 consecutive days. Cure was assessed 5 weeks after treatment and 79.4% of the first group and 93.9% of the second group were cured. The drug was well tolerated; no serious side-effects were noted. One patient developed biochemical cholestasis the third day after treatment, but her enzyme profiles returned to normal after 2 months. We conclude triclabendazole is a safe and potent fasciolicidic drug
El Morshedy, H., Farghaly, A., Sharaf, S., Abou Basha, L. & Barakat, R. (1999). Triclabendazole in the treatment of human fascioliasis: a community-based study. EMHJ - Eastern Mediterranean Health Journal, 5 (5), 888-894, 1999 http://www.who.int/iris/handle/10665/118776
JournalEMHJ - Eastern Mediterranean Health Journal, 5 (5), 888-894, 1999
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