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Relation between serum ferritin and liver and heart MRI T2 in beta thalassaemia major patients

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Abstract
There is a need for higly accurate non-invasive methods for assessing organ iron content in thalassaemia patients. This study evaluated the relation between serum ferritin level, liver enzyme levels and hepatitis C antibody and liver and heart iron deposition assessed by MRI T2 Data were obtained from the medical records of 156 thalassemia major patients in Tehran. There was a moderate negative correlation between serum ferritin and liver MRI T2 relaxation time [‎r= -0.535]‎ and a weak negative correlation between serum ferritin and heart MRI T2 relaxation time [‎r= -0.361]‎. Hepatitis C infection and liver enzyme levels did not confound or modify the relation between ferritin and liver or heart MRI T2. Liver and heart MRI T2* readings were poorly correlated [‎r= 0. 281]‎. Routine evaluation of liver and heart iron content using MRI T2 is suggested to better evaluate the haemosiderosis status in thalassemia patients
Citation
Azarkeivan, A., Hashemieh, M., Akhlaghpoor, S., Shirkavand, A., Yaseri, M. et al. (‎2013)‎. Relation between serum ferritin and liver and heart MRI T2 in beta thalassaemia major patients. EMHJ - Eastern Mediterranean Health Journal, 19 (‎8)‎, 727 - 732, 2013 https://apps.who.int/iris/handle/10665/118533
Journal
EMHJ - Eastern Mediterranean Health Journal, 19 (‎8)‎, 727 - 732, 2013
Description
727 - 732
ISSN
1020-3397
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English
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  • EMRO Journal Articles (‎EMHJ)‎
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