Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases
AbstractThis study was designed to estimate interferon-gamma [INF-gamma] levels among polytransfused haematology cases. Cases were selected from the haematology unit of Alexandria main university hospital, Egypt. Complete blood counts, estimation of INF-gamma and hepatitis B and C virus [HBV and HCV] status were conducted on 20 unsplenectomized patients with thalassaemia major and 20 patients with acute myeloid leukaemia [AML] in the maintenance phase and 20 healthy subjects. Mean haemoglobin levels and red blood cell counts were significantly higher in the control group than the AML and thalassaemia groups, while white blood cell counts were significantly lower in the control group than the case groups. Two AML patients [10%] and 1 thalassaemia patient [5%] were HBV-positive, while 5% of both case groups were HCV-positive. Mean values of INF-? were significantly different between AML, thalassaemia major and control groups: 5517 [SD 1142] pg/mL, 1024 [SD 249] pg/mL and 2980 [SD 604] pg/mL respectively
Roshdy, M.N., Harfoush, R.A., Hamed, N.A. & Morsi, M.G. (2013). Quantitative estimation of interferon-gamma levels among Egyptian polytransfused haematology cases. EMHJ - Eastern Mediterranean Health Journal, 19 (5), 490 - 494, 2013 http://www.who.int/iris/handle/10665/118381
JournalEMHJ - Eastern Mediterranean Health Journal, 19 (5), 490 - 494, 2013
Description490 - 494
MetadataShow full item record
Showing items related by title and MeSH subject.
Noorbakhsh, S.; Mousavi, J.; Barati, M.; Shamshiri, A.R.; Shekarabi, M.; Tabatabaei, A.; Soleimani, Gh. (2011)In a cross-sectional study in a hospital in Tehran in 2006-08 the QuantiFERON[Registered]-TB interferon-gamma release assay [QTB] was compared with the tuberculin skin test [TST] in 59 young people [aged<20 years] with close contact with immunocompetent cases of proven pulmonary tuberculosis. After 1 year follow-up 10 subjects had progressed to tuberculosis disease and received treatment; TST was positive in 30% and QTB in 100%. Of the 49 non-progressive subjects, TST was positive in 10.4% and QTB in 16.3%. The agreement between TST and QTB assay ...
Interferon-gamma release assay for detection of latent tuberculosis infection in casual and close contacts of tuberculosis cases Abu Taleb, A.M.F.; El Sokkary, R.H.; El Tarhouny, S.A. (2011)The tuberculin skin test [TST] has many limitations for the diagnosis of latent tuberculosis [TB] infection. The aim of this study in Egypt was to estimate the usefulness of an interferon-gamma release assay [IFN-gamma] assay for the detection of latent TB infection in contacts of active TB cases. A total of 116 participants were enrolled and divided into 3 groups: community controls, casual [laboratory and clinic] contacts and close [household] contacts. Subjects diagnosed with latent TB infection by TST were 11.5% of controls, 71.1% of casual ...