Eosinophilic cationic protein: is it useful in assessing control of childhood asthma?
AbstractThis study evaluated peripheral eosinophil and serum eosinophilic cationic protein [s-ECP] levels as markers of asthma control. A total of 38 children with asthma [16 controlled and 22 partially controlled] were compared with 16 age- and sex-matched healthy children. Total asthma cases had higher eosinophil counts and s-ECP levels than healthy children and partially controlled asthmatics had significantly higher levels of both markers than controlled asthmatics. Controlled asthma cases showed non-significant changes in both parameters versus healthy children. A negative correlation was noted between degree of asthma control and both eosinophil counts and s-ECP levels [r = -0.60 and -0.75 respectively]. s-ECP as well as peripheral eosinophil count may be helpful in the assessment of asthma control
Zedan, M., Settin, A., El Chennawi, F., El Desouky, T., Nasef, N. et al. (2010). Eosinophilic cationic protein: is it useful in assessing control of childhood asthma?. EMHJ - Eastern Mediterranean Health Journal, 16 (10), 1045-1049, 2010 https://apps.who.int/iris/handle/10665/118001