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dc.contributor.authorRahmo, A.
dc.contributor.authorHamze, M.
dc.date.accessioned2014-06-17T09:13:58Z
dc.date.available2014-06-17T09:13:58Z
dc.date.issued2010EN
dc.identifier.issn1020-3397EN
dc.identifier.otherhttp://applications.emro.who.int/emhj/V16/08/16_8_2010_0820_0830.pdfEN
dc.identifier.urihttp://www.who.int/iris/handle/10665/117945
dc.description820-830EN
dc.description.abstractThe role of previous treatment in the dynamics of tuberculosis transmission has not been adequately investigated. Mycobacterium tuberculosis isolates from previously treated patients [‎n = 88]‎ from all regions of Syrian Arab Republic were characterized in terms of antibiotic sensitivity and genotyping using double-repetitive-element polymerase chain reaction [‎DRE-PCR]‎ method for the proximity of the repetitive DNA elements IS6110 [‎a mobile genetic element]‎ and PGRS. The 88 isolates resulted in 59 different DRE-PCR patterns. Correlations related to age, sex, region, sensitivity and genotype were examined. All regions of the country showed high levels of genotype diversity, suggesting a low level of transmission of M. tuberculosis strains in previously treated patientsEN
dc.language.isoenEN
dc.subjectPolymerase Chain ReactionEN
dc.subjectMycobacterium tuberculosisEN
dc.subjectGenotypeEN
dc.subjectMicrobial Sensitivity TestsEN
dc.subjectTuberculosis, Multidrug-ResistantEN
dc.subject.meshMycobacterium tuberculosisEN
dc.titleCharacterization of Mycobacterium tuberculosis in Syrian patients by double-repetitive-element polymerase chain reactionEN
dc.relation.ispartofjournalEMHJ - Eastern Mediterranean Health Journal, 16 (‎8)‎, 820-830, 2010


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