Evaluation of intralesional 0.2% ciprofloxacin as a treatment for cutaneous leishmaniasis
AbstractAlthough cutaneous leishmaniasis lesions usually heal spontaneously they cause unsightly scarring. This study evaluated a possible new therapy in 38 patients, with 70 lesions, randomly assigned to intralesional injection of ciprofloxacin [0.2%] or intralesional sodium chloride hypertonic solution [7%]. After excluding patients who defaulted on treatment, lesions assigned to sodium chloride treatment [n = 21] were completely healed [with or without scarring] in 76.2% of cases, and, when a scar remained, the scar size was reduced 66.0% compared with the original lesion. Lesions assigned to ciprofloxacin [n = 27] showed an 81.5% healing rate with an average scar size reduction of 68.6%. Intralesional 0.2% ciprofloxacin was as effective as hypertonic saline in the treatment of cutaneous leishmaniasis infection
Al Hamdi, K.I., Awad, A.H. & Moker, H.M. (2010). Evaluation of intralesional 0.2% ciprofloxacin as a treatment for cutaneous leishmaniasis. http://www.who.int/iris/handle/10665/117823
EMHJ - Eastern Mediterranean Health Journal, 16 (1), 89-93, 2010
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