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Biological activity resulting from exposure to aquatic environmental genotoxic pollutants in northern Egypt

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Abstract
We estimated pollution in Lake Edku and the Mediterranean Sea, El-Maadiya Region, with 3 aromatic amines [‎1-naphthylamine, 2-naphthylamine and benzidine]‎ in the muscle tissue of fish. There were marked seasonal variations in the aromatic amine levels. We also determined oxidative stress [‎blood glutathione, and catalase activity]‎ and genotoxic effects [‎chromosomal aberrations and urinary metabolites]‎ in fishermen from each area. The fishermen suffered from oxidative stress and had high levels of the urinary metabolite sulfanilamide [‎mean [‎microg/mg creatinine]‎: Lake Edku 20.7, Mediterranean 14.5, controls 5.3]‎. Frequencies for total chromosomal aberrations were significantly raised in the peripheral blood lymphocytes of fishermen in both areas [‎frequency [‎per 100 metaphases]‎: Mediterranean 67, Lake Edku 45, controls 14]‎
Citation
Saad, A.A., El Sikaily, A.M., Kholeif, S.F., Khalil, E.S., Mahrous, H.S. et al. (‎2010)‎. Biological activity resulting from exposure to aquatic environmental genotoxic pollutants in northern Egypt. EMHJ - Eastern Mediterranean Health Journal, 16 (‎1)‎, 82-88, 2010 https://apps.who.int/iris/handle/10665/117822
Journal
EMHJ - Eastern Mediterranean Health Journal, 16 (‎1)‎, 82-88, 2010
Description
82-88
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/V16/01/16_1_2010_0082_0088.pdf
Language
English
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