Prevalence of factor V Leiden mutation in patients with thrombosis in Tunisia
AbstractThis study determined the prevalence of inherited factor V Leiden mutation in a group of 128 thrombosis patients [102 with venous thrombosis and 26 with arterial thrombosis] attending a hospital in Sousse, Tunisia, and a control group of 100 with no history of thrombosis. Using an allele-specific PCR amplification technique, factor V Leiden was found in significantly more patients [20.3%] than controls [6.0%]. The higher prevalence was significant in the subgroup of venous thrombosis patients but not in arterial thrombosis patients. The allele frequency was 3.5% in the normal Tunisian population. Screening Tunisian patients with venous thrombosis and their relatives for factor V Leiden may be justified
Ajem, A., Slama, A., Slama, F.B.H. & Mehjoub, T. (2009). Prevalence of factor V Leiden mutation in patients with thrombosis in Tunisia. EMHJ - Eastern Mediterranean Health Journal, 15 (6), 1483-1488, 2009 http://www.who.int/iris/handle/10665/117788
JournalEMHJ - Eastern Mediterranean Health Journal, 15 (6), 1483-1488, 2009
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