Adverse drug reactions in an Iranian department of adult infectious diseases

Abstract

This study aimed to assess the frequency and severity of adverse drug reactions [‎ADRs]‎ [‎WHO definition]‎ in hospitalized adult patients in an infectious diseases referral ward in Tehran. Of 281 patients evaluated over 6 months, a total of 170 suspected ADRs were reported among 101 patients [‎35.9%]‎. The most commonly affected organ system was gastrointestinal [‎47.5%]‎, and the most common class of drugs responsible was anti-infectives [‎93.1%]‎. ADRs were high among HIV-positive patients [‎82.9%]‎, mainly due to anti-tuberculosis drugs. Attention to appropriate prescription of drugs is required with more careful clinical and laboratory monitoring of patients