Comparison of the effectiveness of 2 treatment regimens in patients with isoniazid-resistant tuberculosis

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Abstract
We compared the effectiveness of 2 treatment regimens for isoniazid-resistant tuberculosis [TB] in 42 patients attending a TB referral centre in the Islamic Republic of Iran. The patients were divided into 2 treatment groups: 26 received the 6-month standard HRZE treatment and 16 received a modified treatment of RZE for 6 months. There were no significant differences in age or sex of the groups. With the standard method of treatment, 21 [80.8%] patients were cured, 4 [15.4%] resulted in treatment failure, and 1 [3.8%] died. In the modified treatment group, 16 [100%] patients were cured. These differences were not statistically significantly different [P = 0.194]Citation
Tabarsi, P., Baghaei, P., Hemmati, N., Mirsaeidi, M., Kazempour, M. et al. (2009). Comparison of the effectiveness of 2 treatment regimens in patients with isoniazid-resistant tuberculosis. EMHJ - Eastern Mediterranean Health Journal, 15 (6), 1346-1350, 2009 https://apps.who.int/iris/handle/10665/117768