T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy
AbstractThis study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysis
Kamel, L., Morsy, A. & El Shamaa, A. (2009). T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy. EMHJ - Eastern Mediterranean Health Journal, 15 (4), 807-816, 2009 https://apps.who.int/iris/handle/10665/117702
JournalEMHJ - Eastern Mediterranean Health Journal, 15 (4), 807-816, 2009
MetadataShow full item record
Showing items related by title and subject
Urinary N-acetyl-beta-D-glucosaminidase in children with diabetes as an early marker of diabetic nephropathy Abdel Shakour, S.; El Hefnawy, H.; El Yamani, M.Y.; Azmi, Y. (2002)We investigated urinary N-acetyl-beta-D-glucosaminidase [NAG] levels in children with type 1 diabetes as an early marker of tubular damage and studied its correlation with microalbuminuria and glycaemic control. The study ...
Afifi, A.; El Setouhy, M.; El Sharkawy, M.; Ali, M.; Ahmed, H.; El Menshawy, O.; Masoud, W. (2004)The prevalence of diabetic nephropathy as a cause of end-stage renal disease [ESRD] in Egypt has been examined in small cross-sectional studies, with conflicting results. The need for a large-scale study prompted us to ...