T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy
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Abstract
This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [biomarkers of inflammatory changes] and soluble biomarkers sICAM-1 and sE-selectin [biomarkers of endothelial dysfunction] in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [DN] and end-stage renal disease [ESRD] compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysisCitation
(2009). T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy. http://www.who.int/iris/handle/10665/117702
Relation
EMHJ - Eastern Mediterranean Health Journal, 15 (4), 807-816, 2009
Description
807-816ISSN
1020-3397Other Identifiers
http://applications.emro.who.int/emhj/1504/15_4_2009_0807_0816.pdfCollections
Language
EnglishMetadata
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