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T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy

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Abstract
This study assessed changes in serum levels of cytokines IFNgamma and IL-10 [‎biomarkers of inflammatory changes]‎ and soluble biomarkers sICAM-1 and sE-selectin [‎biomarkers of endothelial dysfunction]‎ in diabetic patients with and without nephropathy. IFNgamma and IL-10 were significantly elevated in patients with diabetic nephropathy [‎DN]‎ and end-stage renal disease [‎ESRD]‎ compared with controls and diabetic patients without DN. IFNgamma and IL-10 levels were significantly increased after haemodialysis. sICAM-1 and sE-selectin were significantly higher in diabetic, DN and ESRD groups compared with controls, and sICAM-1 but not sE-selectin was increased after haemodialysis
Citation
Kamel, L., Morsy, A. & El Shamaa, A. (‎2009)‎. T-cell cytokine production and endothelial dysfunction in type 2 diabetic patients with nephropathy. EMHJ - Eastern Mediterranean Health Journal, 15 (‎4)‎, 807-816, 2009 https://apps.who.int/iris/handle/10665/117702
Journal
EMHJ - Eastern Mediterranean Health Journal, 15 (‎4)‎, 807-816, 2009
Description
807-816
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/1504/15_4_2009_0807_0816.pdf
Language
English
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