JavaScript is disabled for your browser. Some features of this site may not work without it.
Get the latest COVID-19 technical guidance, scientific and policy briefs here.✕
    • العربية
    • 中文
    • English
    • français
    • русский
    • español
    • Deutsch
    • português
English
  • العربية
  • 中文
  • English
  • français
  • русский
  • español
  • Deutsch
  • português
  • Home
  • Contact
  • Help

Browse

All of IRISCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

Statistics

Most PopularBy Country

Related Links

PAHO IRIS

Carrier detection of phenylketonuria in Iranian families by variable number tandem-repeat polymorphism analysis

Thumbnail
View/Open
14_6_2008_1445_1451.pdf (‎580.0Kb)‎
View Statistics
Show Statistical Information
Altmetrics
Share
  • CSV
  • Excel
  • BibTeX
  • RIS
Abstract
This study of Iranian families assessed the usefulness of carrier detection of phenylketonuria by variable number tandem-repeat [‎VNTR]‎ polymorphism analysis. We studied 171 people [‎45 unrelated PKU subjects, and their parents and unaffected siblings]‎. Of 342 chromosomes [‎131 non-PKU and 211 PKU]‎, 5 VNTR alleles were identified. This VNTR system would yield a polymorphism information content of 66%, comparable to that in Europeans and higher than in Chinese. Carrier detection by segregation analysis of VNTR was informative in 89.5% of siblings. We conclude that this polymorphism is highly informative in carrier detection of PKU in the Iranian population
Citation
Hosseini Mazinani, S.M., Koochmeshgi, J., Khazaee Koohpar, Z., Hosein Pur Nobari, N. & Seifati, S.M. (‎2008)‎. Carrier detection of phenylketonuria in Iranian families by variable number tandem-repeat polymorphism analysis. EMHJ - Eastern Mediterranean Health Journal, 14 (‎6)‎, 1445-1451, 2008 https://apps.who.int/iris/handle/10665/117576
Journal
EMHJ - Eastern Mediterranean Health Journal, 14 (‎6)‎, 1445-1451, 2008
Description
1445-1451
ISSN
1020-3397
Other Identifiers
http://applications.emro.who.int/emhj/1406/14_6_2008_1445_1451.pdf
Language
English
Collections
  • EMRO Journal Articles (‎EMHJ)‎
Metadata
Show full item record

Show Statistical Information

View Item 
  • IRIS Home
  • 4. Regional Office for the Eastern Mediterranean
  • EMRO Journal Articles (‎EMHJ)‎
  • View Item
  • IRIS Home
  • 4. Regional Office for the Eastern Mediterranean
  • EMRO Journal Articles (‎EMHJ)‎
  • View Item

© 2021 WHO