Serum endostatin and vascular endothelial growth factor levels in patients with pre-eclampsia
AbstractWe evaluated the prognostic value of serum endostatin and vascular endothelial growth factor [VEGF] for diagnosis of pre-eclampsia. We determined VEGF and endostatin levels in the sera of 20 healthy, non-pregnant women and 64 pregnant women: 20 healthy, 20 with mild pre-eclampsia and 24 with severe pre-eclampsia. Serum levels of these factors in non-pregnant women were similar to those in healthy pregnant women. However, serum levels were significantly higher with mild or severe pre-eclampsia compared with normal pregnancies and significantly higher with severe rather than with mild pre-eclampsia. Elevated levels significantly increased risk more than severity of pre-eclampsia. VEGF and endostatin could be used to differentiate between pre-eclamptic and normal pregnancies and to discriminate mild pre-eclampsia from severe pre-eclampsia
Mahmound, R.A.K. & Abdel Raouf, M. (2006). Serum endostatin and vascular endothelial growth factor levels in patients with pre-eclampsia. EMHJ - Eastern Mediterranean Health Journal, 12 (1-2), 178-187, 2006 http://www.who.int/iris/handle/10665/117069
JournalEMHJ - Eastern Mediterranean Health Journal, 12 (1-2), 178-187, 2006
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