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Sickle-Cell Disease in the African Region: Current Situation and the Way Forward Report of the Regional Director (AFR-RC56-17, 2006)Sickle-cell disease is a genetic blood disorder that affects the haemoglobin within the red blood cells. The recurrent pain and complications caused by the disease can interfere with many aspects of the patient’s life, including education, employment and psychosocial development. Neonatal screening for the sickle-cell trait, when linked to timely diagnostic testing, parental education and comprehensive care, can markedly reduce morbidity and mortality from the disease in infancy and early childhood. 2. In most of the countries where sickle-cell ...