• Prevalence of factor V Leiden mutation in patients with thrombosis in Tunisia 

      مؤلف غير معروف (‏2009)‏
      This study determined the prevalence of inherited factor V Leiden mutation in a group of 128 thrombosis patients [‏102 with venous thrombosis and 26 with arterial thrombosis]‏ attending a hospital in Sousse, Tunisia, and a control group of 100 with no history of thrombosis. Using an allele-specific PCR amplification technique, factor V Leiden was found in significantly more patients [‏20.3%]‏ than controls [‏6.0%]‏. The higher prevalence was significant in the subgroup of venous thrombosis patients but not in arterial thrombosis patients. The allele ...