Now showing items 1-3 of 3

    • Characterization of influenza outbreaks in Lebanon during the 2013/14 and 2014/15 seasons 

      Saito, R.; Akinobu, H.; Shaker, R.A.; Akel, I. S.; Assaf Casals, A.; Lteif, M.; Odagiri, T.; Inaba, R.; Soudani, N.; Khafaja, S.; Ghanem, S.T.; Rajab, M.; Shobugawa, Y.; Dbaibo, G.S.; Zaraket, H. (‎2016-07)‎
      Despite the significant burden of influenza outbreaks, active disease monitoring has been largely absent in the Middle East, including Lebanon. In this study we characterized influenza virus in 440 nasopharyngeal swabs collected from patients with acute respiratory infections during two influenza seasons in Lebanon. Influenza A[‎H3N2]‎ was dominant in the 2013/14 season while the A[‎H1N1]‎pdm09 and B/Yamagata strains were most prevalent in the 2014/15 season. All tested isolates were susceptible to 4 neuraminidase inhibitors [‎oseltamivir, zanamivir, ...
    • Detection of influenza B viruses with reduced sensitivity to neuraminidase inhibitor in Morocco during 2014/15 season 

      Elfalki, F.; Ihazmad, H.; Bimouhen, A.; Regragui, Z.; Benkaroum, S.; Bakri, Y.; Barakat, A. (‎2016)‎
      We monitored phenotypic and genotypic susceptibility of influenza viruses circulating in Morocco during 2014-2015 to oseltamivir and zanamivir. Throat and nasal swab specimens were collected from outpatients [‎with influenza-like illness]‎ and inpatients [‎with severe acute respiratory illness]‎ and tested for influenza viruses using real-time reverse transcription polymerase chain reaction. Positive samples were inoculated in MDCK cells and virus phenotypic susceptibility to neuraminidase inhibitors [‎NAIs]‎ was assessed using fluorescent NA inhibition. ...
    • Molecular epidemiology and evolution of A[‎H1N1]‎ pdm09 and H3N2 viruses in Jordan, 2011-2013 

      El Shesheny, R.; Halasa, N.B.; Williams, J.V.; Shehabi, A.A.; Faouri, S.; Kayali, G.; Khuri Bulos, N. (‎2016-07)‎
      Understanding the genetic evolution of A [‎H1N1]‎pdm09 and H3N2 viruses can help better select strains to be included in the annual influenza vaccine. There is little information on their evolution in Jordan so this study investigated the genetic and antigenic variability of A[‎H1N1]‎pdm09 and H3N2 viruses in Jordan by performing phylogenetic and genetic analyses of the HA and NA genes of A[‎H1N1]‎pdm09 and H3N2 viruses between 2011 and 2013. The full HA and NA genes of 16 H1N1-positive samples obtained in our study and 21 published HA sequences and ...