Browsing by Subject "Drug Toxicity"
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(2009)This study aimed to assess the frequency and severity of adverse drug reactions [ADRs] [WHO definition] in hospitalized adult patients in an infectious diseases referral ward in Tehran. Of 281 patients evaluated over 6 months, a total of 170 suspected ADRs were reported among 101 patients [35.9%]. The most commonly affected organ system was gastrointestinal [47.5%], and the most common class of drugs responsible was anti-infectives [93.1%]. ADRs were high among HIV-positive patients [82.9%], mainly due to anti-tuberculosis drugs. Attention to ...
Prevalence and preventability of adverse drug events in a teaching hospital: a cross-sectional study (2009)We determined the prevalence of adverse drug events [ADEs] in a general teaching hospital in Rabat, Morocco. We performed a 5-day cross-sectional study of hospital departments recruiting inpatients and outpatients. Among the 1390 patients surveyed, 59 [4.2%] experienced at least 1 ADE and for 20 patients [1.4%] the ADE was responsible for hospitalization or prolongation of hospitalization. The ADE was classified as serious in 28 patients. Of the total of 76 ADEs, 10 [13.2%] were categorized as preventable; 6 of these occurred during the treatment ...