XANTHAN GUM

Overview

CAS number
11138-66-2
INS
415
Functional Class
Food Additives
EMULSIFIER
FOAMING_AGENT
STABILIZER
THICKENER
INS matches
415

Evaluations

Evaluation year: 2016

ADI:
NOT SPECIFIED

Comments:
A NOAEL of 750 mg/kg bw per day was established for xanthan gum in neonatal pigs, which are an appropriate animal model for the assessment of the safety of the additive for infants. The margin of exposure based on this NOAEL and the conservative estimate of xanthan gum intake of 220 mg/kg bw per day by infants (high energy requirements for fully formula-fed infants) is 3.4. On the basis of a number of considerations, JECFA concluded that the consumption of xanthan gum in infant formula or formula for special medical purposes intended for infants is of no safety concern at the maximum proposed use level of 1000 mg/L.
Meeting:
82
Specs Code:
R
Report: 
">TRS 1000-JECFA 82/72
Tox Monograph: 
FAS 73 JECFA 82/269
Specification: 
">FAO JECFA Monographs 19/116

Evaluation year: 1986

ADI:
NOT SPECIFIED
Meeting:
30
Specs Code:
R (1993)
Report: 
TRS 751-JECFA 30/27; see also TRS 891-JECFA 51/2 (1998)
Tox Monograph: 
FAS 21-JECFA 30/151
Specification: 
COMPENDIUM ADDENDUM 7/FNP 52 Add.7/105 (1999). R; FAO JECFA Monographs 1 vol.3/589
Previous Years:
1998, COMPENDIUM ADDENDUM 6/FNP 52 Add.6/165. R 1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/135. R 1990, COMPENDIUM/1581. R 1988, FNP 38-JECFA 33/263. R,T 1986, FNP 37-JECFA 30/149. R 1985, TRS 733-JECFA 29/38, FNP 34-JECFA 29/233, FAS 6/NMRS 54A-JECFA
1998, COMPENDIUM ADDENDUM 6/FNP 52 Add.6/165. R 1993, COMPENDIUM ADDENDUM 2/FNP 52 Add.2/135. R 1990, COMPENDIUM/1581. R 1988, FNP 38-JECFA 33/263. R,T 1986, FNP 37-JECFA 30/149. R 1985, TRS 733-JECFA 29/38, FNP 34-JECFA 29/233, FAS 6/NMRS 54A-JECFA