POLYVINYL ALCOHOL (PVA) – POLYETHYLENE GLYCOL (PEG) GRAFT CO-POLYMER

Comments:

Based on these data, the Committee would normally establish an ADI “not specified”. However, the Committee decided not to establish an ADI “not specified” for PVA-PEG graft copolymer in view of the impurities present, some of which may also be impurities in other food additives. The Committee had concerns that establishing an ADI “not specified” could lead to additional uses beyond those considered in the present evaluation and consequently could increase exposure to the impurities. The Committee concluded that the use of PVA-PEG graft co-polymer that complies with the specifications established at the current meeting is not of safety concern when the food additive is used as a glazing agent (aqueous film coating), stabilizer and binder for tablets in the preparation and formulation of food supplements and in accordance with good manufacturing practice.

Intake:

The use of PVA-PEG graft copolymer that complies with the proposed specifications could lead to dietary exposure to vinyl acetate from both food supplements and pharmaceutical products up to 0.0008 mg/kg bw per day for children.

Meeting:

80

Specs Code:

N

Report: 

Tox Monograph: 

Specification: