2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE
Overview
Chemical Names
2-ISOPROPYL-N,2,3-TRIMETHYLBUTYRAMIDE
Synonyms
N,2,3-TRIMETHYL-2-ISOPROPYLBUTANAMIDE; METHYL DIISOPROPYL PROPIONAMIDE; 6-CAPROLACTAM
CAS number
51115-67-4
JECFA number
1595
COE number
16053
FEMA number
3804
Functional Class
Flavouring Agent
FLAVOURING_AGENT
FLAVOURING_AGENT
Evaluations
Evaluation year: 2016
Comments:
Additional data required to complete evaluation. Concerns for in vivo genotoxicity and kidney effects at low doses.
Meeting:
82
Report:
Tox Monograph:
Evaluation year: 2008
Comments:
Intake estimate exceeds the TTC of 90 µg/person per day for the class, hence requiring a re-evaluation.
Meeting:
69
Specs Code:
S
Report:
Tox Monograph:
Specification:
Evaluation year: 2005
ADI:
ACCEPTABLE (CONDITIONAL)
Comments:
No safety concern (conditional) at current levels of intake when used as a flavouring agent. The evaluation is conditional because the estimated daily intake is based on the anticipated annual volume of production. The conclusion of the safety evaluation of this substance will be revoked if use levels or poundage data are not provided before the end of 2007.
Report:
Tox Monograph:
Specification: